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Some clinical studies have shown detrimental effects of DPP-4 inhibitors on bone [13, 16, 18], with one study showing no effects [110]
Vitamin B12 also helps prevent megaloblastic anemia, which makes people tired and weak
This suggests that the dose-escalation schedule used for the 36 mg arm may have been somewhat better optimized to mitigate nausea than the schedule for the 12 mg arm, or that the higher dose groups achieved better gastrointestinal adaptation during the titration period
Millions of Americans struggle with weight loss, often trying numerous methods without success, which can lead to a decline in self-efficacy
Cho SG, Lee YH, Park HS, Ryoo K, Kang KW, Park J, Eom SJ, Kim MJ, Chang TS, Choi SY, Shim J, Kim Y, Dong MS, Lee MJ, Kim SG, Ichijo H and Choi EJ
